Hundred thousand genomes to be mapped in Saudi Arabia
Saudi Arabia is launching a national research project to study the genetic basis of disease in its population
Up to 100,000 people in Saudi Arabia are to have their genetic codes mapped in a new human genome project.
The research will look at genes linked with diseases, and pave the way for prenatal and premarital screening.
The project, funded by the Saudi Arabian national science agency, will create a DNA database to develop personalised medicine.
A similar UK scheme is under way to map the genomes of 100,000 NHS patients.
Genome studies are moving from analysing the personal DNA
code of individuals for research purposes, to clinical applications,
such as treatments tailored to the genetic makeup of cancers.
“I hope to see broader engagement between Western countries and Middle Eastern countries in this area, and data sharing and expertise sharing in both directions”
Dr Ewan Birney European Molecular Biology Laboratory -European Bioinformatics Institute
The Saudi effort will focus on
sequencing 100,000 human genomes over the next five years to study both
normal genes and those linked to disease.
King Abdulaziz City for Science and Technology president Dr
Mohammed Bin Ibrahim Al Suwayl said: "We have clear strategy and policy
of the importance of science to a knowledge-based society and we believe
the Saudi human genome programme will help shape the understanding of
health and disease and usher in an era of personalised medicine in the
Kingdom of Saudi Arabia and we are grateful for the investment and
vision of the Saudi leadership."
The research will take place at 10 genome centres across
Saudi Arabia, with another five genome centres to be created in coming
years.
UK genome expert Dr Ewan Birney, said while big genetic
differences between Middle Eastern populations and populations outside
the Middle East were unlikely, there may be a slightly different
spectrum of genetic diseases in Saudi Arabia.
Commenting on the announcement of the project, Dr Birney,
associate director at the European Molecular Biology Laboratory -
European Bioinformatics Institute, said: "I'm excited that Saudi Arabia
is taking a substantial step forward in sequencing genomes in their
clinical healthcare.
"I hope to see broader engagement between Western countries
and Middle Eastern countries in this area, and data sharing and
expertise sharing in both directions."
A number of genome sequencing efforts are under way around
the world. They include the 1,000 genomes project, an international
research effort to look at human genetic variation.
The UK is to map the genomes of up to 100,000 NHS patients
with cancer and rare diseases by 2017 in a £100m effort funded by the
government.